Nambari ya Glybenclamide Cas: 10238-21-8 Mfumo wa Masi:C23H28ClN3O5S
5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]SULPHONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE
GIBENCLAMIDE
GLIBENCLAMIDE
GLYBENCLAMIDE
GLYBENZCYCLAMIDE
GLYBURIDE
LABOTEST-BB LT00244861
MICRONASE
NP-[2-(5-CHLORO-2-METHOXYBENZAMIDO)ETHYL]BENZENESULFONYL-N'-CYCLOHEXYLUREA
1-((p-(2-(Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl urea
1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-ure
1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
1-[[p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea
1-[[p-[2-(chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexyl-Urea
5-chloro-n-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2
Abbenclamide
adiab
Kiwango cha kuyeyuka | 173-175°C |
Msongamano | 1.1805 (makadirio mabaya) |
joto la kuhifadhi | Hali ya anga isiyo na hewa, Joto la Chumba 2-8°C |
umumunyifu | ethanoli: mumunyifu2mg/mL |
shughuli ya macho | N/A |
Mwonekano | Poda Nyeupe ya Fuwele |
Usafi | ≥98% |
Glyburide (10238-21-8) ni wakala wa pili wa mdomo wa hypoglycemic.Hufanya kazi kupitia chaneli ya K+ inayotegemewa na ATP (Kir6, KATP) kuzuia.1?Huzuia mikondo ya Kir6 kwenye kongosho, na kusababisha ongezeko la Ca2+ ndani ya seli na utolewaji wa insulini.Glyburide pia huzuia chaneli za CFTR Cl- recombinant na IC50 ya 20 μM.2?Cell inayopenyeza.
Kizazi cha pili cha sulfonylurea na shughuli ya hypoglycemic
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